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Carbonic anhydrase inhibition with a series of novel benzenesulfonamide-triazole conjugates

We report the synthesis and characterisation of a novel series of triazole benzenesulfonamide derivatives, which incorporate the general pharmacophore associated with carbonic anhydrase (CA, EC 4.2.1.1) inhibitors. The synthesised compounds were tested in vitro against four human carbonic anhydrase...

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書誌詳細
出版年:J Enzyme Inhib Med Chem
主要な著者: El-Gazzar, Marwa G., Nafie, Nessma H., Nocentini, Alessio, Ghorab, Mostafa M., Heiba, Helmi I., Supuran, Claudiu T.
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171417/
https://ncbi.nlm.nih.gov/pubmed/30274535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1513927
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