Differential Effects of Inhibitory and Stimulatory Anti-HER2 Monoclonal Antibodies on AKT/ERK Signaling Pathways

OBJECTIVE: Homo- and heterodimerization of the receptor tyrosine kinase HER2 hyperactivate several downstream signaling pathways, leading to uncontrolled growth and proliferation of tumor cells. Anti-HER2 monoclonal antibodies (mAbs) may induce different effects on HER2 dimerization and signaling. M...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Asian Pac J Cancer Prev
Auteurs principaux: Soltantoyeh, Tahereh, Bahadori, Tannaz, Hosseini-Ghatar, Reza, Khoshnoodi, Jalal, Roohi, Azam, Mobini, Maryam, Golsaz-Shirazi, Forough, Jeddi-Tehrani, Mahmood, Amiri, Mohammad Mehdi, Shokri, Fazel
Format: Artigo
Langue:Inglês
Publié: West Asia Organization for Cancer Prevention 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171393/
https://ncbi.nlm.nih.gov/pubmed/30139234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22034/APJCP.2018.19.8.2255
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires