A Novel Anti-HER2 Bispecific Antibody With Potent Tumor Inhibitory Effects In Vitro and In Vivo

Overexpression of HER2 has been reported in many types of cancer, making it a perfect candidate for targeted immunotherapy. The combination of two FDA approved monoclonal antibodies (mAbs), trastuzumab and pertuzumab, has more robust anti-tumor activity in patients with HER2-overexpressing breast ca...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mohammadi, Mehdi, Jeddi-Tehrani, Mahmood, Golsaz-Shirazi, Forough, Arjmand, Mohammad, Bahadori, Tannaz, Judaki, Mohammad Ali, Shiravi, Fariba, Zare, Hengameh Ahmadi, Haghighat, Farzaneh Notash, Mobini, Maryam, Amiri, Mohammad Mehdi, Shokri, Fazel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927792/
https://ncbi.nlm.nih.gov/pubmed/33679691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.600883
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