Early Growth Response Gene-1 Suppresses Foot-and-Mouth Disease Virus Replication by Enhancing Type I Interferon Pathway Signal Transduction

Early growth response gene-1 (EGR1) is a multifunctional transcription factor that is implicated in viral infection. In this study, we observed that foot-and-mouth disease virus (FMDV) infection significantly triggered EGR1 expression. Overexpression of EGR1 suppressed FMDV replication in porcine ce...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Main Authors: Zhu, Zixiang, Du, Xiaoli, Li, Pengfei, Zhang, Xiangle, Yang, Fan, Cao, Weijun, Tian, Hong, Zhang, Keshan, Liu, Xiangtao, Zheng, Haixue
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170816/
https://ncbi.nlm.nih.gov/pubmed/30319594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.02326
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