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Effects of Branched-Chain Amino Acid Supplementation on Spontaneous Seizures and Neuronal Viability in a Model of Mesial Temporal Lobe Epilepsy

BACKGROUND: The essential branched-chain amino acids (BCAAs) leucine, isoleucine and valine have recently emerged as a potential novel treatment for medically-refractory epilepsy. Blood-derived BCAAs can readily enter the brain, where they contribute to glutamate biosynthesis and may either suppress...

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Dettagli Bibliografici
Pubblicato in:J Neurosurg Anesthesiol
Autori principali: Gruenbaum, Shaun E., Dhaher, Roni, Rapuano, Amedeo, Zaveri, Hitten P., Tang, Amber, de Lanerolle, Nihal, Eid, Tore
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170745/
https://ncbi.nlm.nih.gov/pubmed/29620688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ANA.0000000000000499
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