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Ryanodine Receptor Open Times Are Determined in the Closed State

The ryanodine receptor (RyR) ion channel releases Ca(2+) from intracellular stores by conducting Ca(2+) but also by recruiting neighboring RyRs to open, as RyRs are activated by micromolar levels of cytosolic Ca(2+). Using long single-RyR recordings of the cardiac isoform (RyR2), we conclude that Ca...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Fill, Michael, Gillespie, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170654/
https://ncbi.nlm.nih.gov/pubmed/30220413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.08.025
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