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Ryanodine Receptor Current Amplitude Controls Ca(2+) Sparks in Cardiac Muscle

RATIONALE: In cardiac muscle, Ca(2+) induced Ca(2+) release (CICR) from the sarcoplasmic reticulum (SR) is mediated by ryanodine receptor (RyR) Ca(2+) release channels. The inherent positive feedback of CICR is normally well controlled. Understanding this control mechanism is a priority because its...

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Detalhes bibliográficos
Main Authors: Guo, Tao, Gillespie, Dirk, Fill, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417769/
https://ncbi.nlm.nih.gov/pubmed/22628577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.265652
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