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Unitary Ca(2+) Current through Mammalian Cardiac and Amphibian Skeletal Muscle Ryanodine Receptor Channels under Near-physiological Ionic Conditions

Ryanodine receptor (RyR) channels from mammalian cardiac and amphibian skeletal muscle were incorporated into planar lipid bilayers. Unitary Ca(2+) currents in the SR lumen-to-cytosol direction were recorded at 0 mV in the presence of caffeine (to minimize gating fluctuations). Currents measured wit...

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Detalhes bibliográficos
Main Authors: Kettlun, Claudia, González, Adom, Ríos, Eduardo, Fill, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233776/
https://ncbi.nlm.nih.gov/pubmed/12975450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200308843
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