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Physiologic Gating Properties of Unitary Cardiac L-Type Ca(2+) Channels

The contraction of adult mammalian ventricular cardiomyocytes is triggered by the influx of Ca(2+) ions through sarcolemmal L-type Ca(2+) channels (LCCs). However, the gating properties of unitary LCCs under physiologic conditions have remained elusive. Towards this end, we investigated the voltage-...

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Autores principales: Josephson, Ira R., Guia, Antonio, Sobie, Eric A., Lederer, W. Jonathan, Lakatta, Edward G., Stern, Michael D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892242/
https://ncbi.nlm.nih.gov/pubmed/20457123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.05.016
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