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Ca(2+)-dependent components of inactivation of unitary cardiac L-type Ca(2+) channels

A Ca(2+) ion-dependent inactivation (CDI) of L-type Ca(2+) channels (LCC) is vital in limiting and shaping local Ca(2+) ion signalling in a variety of excitable cell types. However, under physiological conditions the unitary LCC properties that underlie macroscopic inactivation are unclear. Towards...

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Detalhes bibliográficos
Main Authors: Josephson, Ira R, Guia, Antonio, Lakatta, Edward G, Lederer, W Jonathan, Stern, Michael D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821560/
https://ncbi.nlm.nih.gov/pubmed/19917566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.178343
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