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Ca(2+)-dependent components of inactivation of unitary cardiac L-type Ca(2+) channels

A Ca(2+) ion-dependent inactivation (CDI) of L-type Ca(2+) channels (LCC) is vital in limiting and shaping local Ca(2+) ion signalling in a variety of excitable cell types. However, under physiological conditions the unitary LCC properties that underlie macroscopic inactivation are unclear. Towards...

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Détails bibliographiques
Auteurs principaux: Josephson, Ira R, Guia, Antonio, Lakatta, Edward G, Lederer, W Jonathan, Stern, Michael D
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821560/
https://ncbi.nlm.nih.gov/pubmed/19917566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.178343
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