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Energetics of Divalent Selectivity in a Calcium Channel: The Ryanodine Receptor Case Study

A model of the ryanodine receptor (RyR) calcium channel is used to study the energetics of binding selectivity of Ca(2+) versus monovalent cations. RyR is a calcium-selective channel with a DDDD locus in the selectivity filter, similar to the EEEE locus of the L-type calcium channel. While the affin...

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Detalhes bibliográficos
Autor principal: Gillespie, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212702/
https://ncbi.nlm.nih.gov/pubmed/17951303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.116798
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