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Energetics of Divalent Selectivity in a Calcium Channel: The Ryanodine Receptor Case Study
A model of the ryanodine receptor (RyR) calcium channel is used to study the energetics of binding selectivity of Ca(2+) versus monovalent cations. RyR is a calcium-selective channel with a DDDD locus in the selectivity filter, similar to the EEEE locus of the L-type calcium channel. While the affin...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212702/ https://ncbi.nlm.nih.gov/pubmed/17951303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.116798 |
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