Insulin regulates POMC neuronal plasticity to control glucose metabolism

Hypothalamic neurons respond to nutritional cues by altering gene expression and neuronal excitability. The mechanisms that control such adaptive processes remain unclear. Here we define populations of POMC neurons in mice that are activated or inhibited by insulin and thereby repress or inhibit hep...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Dodd, Garron T, Michael, Natalie J, Lee-Young, Robert S, Mangiafico, Salvatore P, Pryor, Jack T, Munder, Astrid C, Simonds, Stephanie E, Brüning, Jens Claus, Zhang, Zhong-Yin, Cowley, Michael A, Andrikopoulos, Sofianos, Horvath, Tamas L, Spanswick, David, Tiganis, Tony
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Human Biology and Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170188/
https://ncbi.nlm.nih.gov/pubmed/30230471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38704
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