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Insulin signaling in AgRP neurons regulates meal size to limit glucose excursions and insulin resistance
The importance of hypothalamic insulin signaling on feeding and glucose metabolism remains unclear. We report that insulin acts on AgRP neurons to acutely decrease meal size and thereby limit postprandial glucose and insulin excursions. The promotion of insulin signaling in AgRP neurons decreased me...
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| Publicado no: | Sci Adv |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7909880/ https://ncbi.nlm.nih.gov/pubmed/33637536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abf4100 |
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