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Loss of Ccbe1 affects cardiac-specification and cardiomyocyte differentiation in mouse embryonic stem cells

Understanding the molecular pathways regulating cardiogenesis is crucial for the early diagnosis of heart diseases and improvement of cardiovascular disease. During normal mammalian cardiac development, collagen and calcium-binding EGF domain-1 (Ccbe1) is expressed in the first and second heart fiel...

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Bibliographic Details
Published in:PLoS One
Main Authors: Bover, Oriol, Justo, Tiago, Pereira, Paulo N. G., Facucho-Oliveira, João, Inácio, José M., Ramalho, José S., Domian, Ibrahim J., Belo, José António
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169972/
https://ncbi.nlm.nih.gov/pubmed/30281646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205108
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