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Loss of Ccbe1 affects cardiac-specification and cardiomyocyte differentiation in mouse embryonic stem cells

Understanding the molecular pathways regulating cardiogenesis is crucial for the early diagnosis of heart diseases and improvement of cardiovascular disease. During normal mammalian cardiac development, collagen and calcium-binding EGF domain-1 (Ccbe1) is expressed in the first and second heart fiel...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bover, Oriol, Justo, Tiago, Pereira, Paulo N. G., Facucho-Oliveira, João, Inácio, José M., Ramalho, José S., Domian, Ibrahim J., Belo, José António
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169972/
https://ncbi.nlm.nih.gov/pubmed/30281646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205108
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