Integrin-targeted quantitative optoacoustic imaging with MRI correlation for monitoring a BRAF/MEK inhibitor combination therapy in a murine model of human melanoma

PURPOSE: To investigate α(v)β(3)-integrin-targeted optoacoustic imaging and MRI for monitoring a BRAF/MEK inhibitor combination therapy in a murine model of human melanoma. MATERIALS AND METHODS: Human BRAF V600E-positive melanoma xenograft (A375)-bearing Balb/c nude mice (n = 10) were imaged before...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kazmierczak, Philipp M., Burton, Neal C., Keinrath, Georg, Hirner-Eppeneder, Heidrun, Schneider, Moritz J., Eschbach, Ralf S., Heimer, Maurice, Solyanik, Olga, Todica, Andrei, Reiser, Maximilian F., Ricke, Jens, Cyran, Clemens C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169922/
https://ncbi.nlm.nih.gov/pubmed/30281669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204930
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