Monitoring Cell Death in Regorafenib-Treated Experimental Colon Carcinomas Using Annexin-Based Optical Fluorescence Imaging Validated by Perfusion MRI

OBJECTIVE: To investigate annexin-based optical fluorescence imaging (OI) for monitoring regorafenib-induced early cell death in experimental colon carcinomas in rats, validated by perfusion MRI and multiparametric immunohistochemistry. MATERIALS AND METHODS: Subcutaneous human colon carcinomas (HT-...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Kazmierczak, Philipp M., Burian, Egon, Eschbach, Ralf, Hirner-Eppeneder, Heidrun, Moser, Matthias, Havla, Lukas, Eisenblätter, Michel, Reiser, Maximilian F., Nikolaou, Konstantin, Cyran, Clemens C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578959/
https://ncbi.nlm.nih.gov/pubmed/26393949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138452
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