(18)F–FDG-PET/CT and diffusion-weighted MRI for monitoring a BRAF and CDK 4/6 inhibitor combination therapy in a murine model of human melanoma

BACKGROUND: The purpose of the study was to investigate a novel BRAF and CDK 4/6 inhibitor combination therapy in a murine model of BRAF-V600-mutant human melanoma monitored by (18)F–FDG-PET/CT and diffusion-weighted MRI (DW-MRI). METHODS: Human BRAF-V600-mutant melanoma (A375) xenograft-bearing bal...

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Detalhes bibliográficos
Publicado no:Cancer Imaging
Main Authors: Eschbach, Ralf S., Kazmierczak, Philipp M., Heimer, Maurice M., Todica, Andrei, Hirner-Eppeneder, Heidrun, Schneider, Moritz J., Keinrath, Georg, Solyanik, Olga, Olivier, Jessica, Kunz, Wolfgang G., Reiser, Maximilian F., Bartenstein, Peter, Ricke, Jens, Cyran, Clemens C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774089/
https://ncbi.nlm.nih.gov/pubmed/29347968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40644-018-0135-y
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