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Exonic splice regulation imposes strong selection at synonymous sites

What proportion of coding sequence nucleotides have roles in splicing, and how strong is the selection that maintains them? Despite a large body of research into exonic splice regulatory signals, these questions have not been answered. This is because, to our knowledge, previous investigations have...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Savisaar, Rosina, Hurst, Laurence D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169883/
https://ncbi.nlm.nih.gov/pubmed/30143596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.233999.117
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