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Activation of podocyte Notch mediates early Wt1 glomerulopathy
The Wilms' tumor suppressor gene, WT1, encodes a zinc finger protein that regulates podocyte development and is highly expressed in mature podocytes. Mutations in the WT1 gene are associated with the development of renal failure due to the formation of scar tissue within glomeruli, the mechanis...
में बचाया:
| में प्रकाशित: | Kidney Int |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Elsevier
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6169130/ https://ncbi.nlm.nih.gov/pubmed/29398135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2017.11.014 |
| टैग : |
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