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Wt1a, Foxc1a, and the Notch mediator Rbpj Physically Interact and Regulate the Formation of Podocytes in Zebrafish

Podocytes help form the glomerular blood filtration barrier in the kidney and their injury or loss leads to renal disease. The Wilms’ tumor suppressor-1 (Wt1) and the FoxC1/2 transcription factors, as well as Notch signaling, have been implicated as important regulators of podocyte fate. It is not k...

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Autori principali: O’Brien, Lori L., Grimaldi, Michael, Kostun, Zachary, Wingert, Rebecca A., Selleck, Rori, Davidson, Alan J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183404/
https://ncbi.nlm.nih.gov/pubmed/21871448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.08.005
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