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A combination antioxidant therapy to inhibit NOX2 and activate Nrf2 decreases secondary brain damage and improves functional recovery after traumatic brain injury

Uncontrolled oxidative stress contributes to the secondary neuronal death that promotes long-term neurological dysfunction following traumatic brain injury (TBI). Surprisingly, both NADPH oxidase 2 (NOX2) that increases and transcription factor Nrf2 that decreases reactive oxygen species (ROS) are i...

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Podrobná bibliografie
Vydáno v:J Cereb Blood Flow Metab
Hlavní autoři: Chandran, Raghavendar, Kim, TaeHee, Mehta, Suresh L, Udho, Eshwar, Chanana, Vishal, Cengiz, Pelin, Kim, HwuiWon, Kim, Chanul, Vemuganti, Raghu
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168911/
https://ncbi.nlm.nih.gov/pubmed/29083257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17738701
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