A combination antioxidant therapy to inhibit NOX2 and activate Nrf2 decreases secondary brain damage and improves functional recovery after traumatic brain injury

Uncontrolled oxidative stress contributes to the secondary neuronal death that promotes long-term neurological dysfunction following traumatic brain injury (TBI). Surprisingly, both NADPH oxidase 2 (NOX2) that increases and transcription factor Nrf2 that decreases reactive oxygen species (ROS) are i...

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Bibliographic Details
Published in:J Cereb Blood Flow Metab
Main Authors: Chandran, Raghavendar, Kim, TaeHee, Mehta, Suresh L, Udho, Eshwar, Chanana, Vishal, Cengiz, Pelin, Kim, HwuiWon, Kim, Chanul, Vemuganti, Raghu
Format: Artigo
Language:Inglês
Published: SAGE Publications 2017
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168911/
https://ncbi.nlm.nih.gov/pubmed/29083257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17738701
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