A combination antioxidant therapy to inhibit NOX2 and activate Nrf2 decreases secondary brain damage and improves functional recovery after traumatic brain injury

Uncontrolled oxidative stress contributes to the secondary neuronal death that promotes long-term neurological dysfunction following traumatic brain injury (TBI). Surprisingly, both NADPH oxidase 2 (NOX2) that increases and transcription factor Nrf2 that decreases reactive oxygen species (ROS) are i...

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Detaylı Bibliyografya
Yayımlandı:J Cereb Blood Flow Metab
Asıl Yazarlar: Chandran, Raghavendar, Kim, TaeHee, Mehta, Suresh L, Udho, Eshwar, Chanana, Vishal, Cengiz, Pelin, Kim, HwuiWon, Kim, Chanul, Vemuganti, Raghu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: SAGE Publications 2017
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168911/
https://ncbi.nlm.nih.gov/pubmed/29083257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17738701
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