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Glutamate-weighted Chemical Exchange Saturation Transfer (GluCEST) Magnetic Resonance Imaging Detects Glutaminase Inhibition in a Mouse Model of Triple Negative Breast Cancer

Glutamate is an important metabolite of glutaminolysis, a metabolic pathway employed by many aggressive cancers including triple-negative breast cancer. With the exception of the brain, in vivo detection of glutamate in tissues using (1)H magnetic resonance spectroscopy (MRS) is challenging. Compare...

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Detaylı Bibliyografya
Yayımlandı:Cancer Res
Asıl Yazarlar: Zhou, Rong, Bagga, Puneet, Nath, Kavindra, Hariharan, Hari, Mankoff, David, Reddy, Ravinder
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168340/
https://ncbi.nlm.nih.gov/pubmed/30072394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-3988
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