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Glutamate-weighted Chemical Exchange Saturation Transfer (GluCEST) Magnetic Resonance Imaging Detects Glutaminase Inhibition in a Mouse Model of Triple Negative Breast Cancer
Glutamate is an important metabolite of glutaminolysis, a metabolic pathway employed by many aggressive cancers including triple-negative breast cancer. With the exception of the brain, in vivo detection of glutamate in tissues using (1)H magnetic resonance spectroscopy (MRS) is challenging. Compare...
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| Veröffentlicht in: | Cancer Res |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6168340/ https://ncbi.nlm.nih.gov/pubmed/30072394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-3988 |
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