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Identification and characterization of prescription drugs that change levels of 7-dehydrocholesterol and desmosterol

Regulating blood cholesterol (Chol) levels by pharmacotherapy has successfully improved cardiovascular health. There is growing interest in the role of Chol precursors in the treatment of diseases. One sterol precursor, desmosterol (Des), is a potential pharmacological target for inflammatory and ne...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Wages, Phillip A., Kim, Hye-Young H., Korade, Zeljka, Porter, Ned A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168312/
https://ncbi.nlm.nih.gov/pubmed/30087204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M086991
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