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Inhibitors of 7-Dehydrocholesterol Reductase: Screening of a Collection of Pharmacologically Active Compounds in Neuro2a Cells

A small library of pharmacologically active compounds (the NIH Clinical Collection) was assayed in Neuro2a cells to determine their effect on the last step in the biosynthesis of cholesterol, the transformation of 7-dehydrocholesterol (7-DHC) to cholesterol promoted by 7-dehydrocholesterol reductase...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Chem Res Toxicol
मुख्य लेखकों: Kim, Hye-Young H., Korade, Zeljka, Tallman, Keri A., Liu, Wei, Weaver, C. David, Mirnics, Karoly, Porter, Ned A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868769/
https://ncbi.nlm.nih.gov/pubmed/27097157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.6b00054
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