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Pink1/Parkin link inflammation, mitochondrial stress, and neurodegeneration

What causes inflammation in age-related neurodegenerative diseases remains a mystery. Sliter et al. (2018. Nature. https://doi.org/10.1038/s41586-018-0448-9) show that, when damaged mitochondria cannot be removed by mitophagy, stress from exercise or mitochondrial DNA mutations activates the proinfl...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Newman, Laura E., Shadel, Gerald S.
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168260/
https://ncbi.nlm.nih.gov/pubmed/30154188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201808118
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