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PINK1/PARKIN signalling in neurodegeneration and neuroinflammation
Mutations in the PTEN-induced kinase 1 (PINK1) and Parkin RBR E3 ubiquitin-protein ligase (PARKIN) genes are associated with familial forms of Parkinson’s disease (PD). PINK1, a protein kinase, and PARKIN, an E3 ubiquitin ligase, control the specific elimination of dysfunctional or superfluous mitoc...
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| Publicat a: | Acta Neuropathol Commun |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7654589/ https://ncbi.nlm.nih.gov/pubmed/33168089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01062-w |
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