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Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel
C-type inactivation is a time-dependent process observed in many K(+) channels whereby prolonged activation by an external stimulus leads to a reduction in ionic conduction. While C-type inactivation is thought to be a result of a constriction of the selectivity filter, the local dynamics of the pro...
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| Pubblicato in: | J Gen Physiol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Rockefeller University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6168234/ https://ncbi.nlm.nih.gov/pubmed/30072373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812082 |
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