Interdependence between EGFR and Phosphatases Spatially Established by Vesicular Dynamics Generates a Growth Factor Sensing and Responding Network

The proto-oncogenic epidermal growth factor receptor (EGFR) is a tyrosine kinase whose sensitivity to growth factors and signal duration determines cellular behavior. We resolve how EGFR's response to epidermal growth factor (EGF) originates from dynamically established recursive interactions w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Syst
Egile Nagusiak: Stanoev, Angel, Mhamane, Amit, Schuermann, Klaus C., Grecco, Hernán E., Stallaert, Wayne, Baumdick, Martin, Brüggemann, Yannick, Joshi, Maitreyi S., Roda-Navarro, Pedro, Fengler, Sven, Stockert, Rabea, Roßmannek, Lisaweta, Luig, Jutta, Koseska, Aneta, Bastiaens, Philippe I.H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167251/
https://ncbi.nlm.nih.gov/pubmed/30145116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2018.06.006
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