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Excess homocysteine upregulates the NRF2-antioxidant pathway in retinal Müller glial cells

This study evaluated the effects of elevated homocysteine (Hcy) on the oxidative stress response in retinal Müller glial cells. Elevated Hcy has been implicated in retinal diseases including glaucoma and optic neuropathy, which are characterized by retinal ganglion cell (RGC) loss. To understand the...

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Bibliografische gegevens
Gepubliceerd in:Exp Eye Res
Hoofdauteurs: Navneet, Soumya, Cui, Xuezhi, Zhao, Jing., Wang, Jing, Ammal Kaidery, Navneet, Thomas, Bobby, Bollinger, Kathryn E., Yoon, Yisang, Smith, Sylvia B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167214/
https://ncbi.nlm.nih.gov/pubmed/29608906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2018.03.022
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