Hyperhomocysteinemia-induced death of retinal ganglion cells: The role of Müller glial cells and NRF2

Hyperhomocysteinemia (Hhcy), or increased levels of the excitatory amino acid homocysteine (Hcy), is implicated in glaucoma, a disease characterized by increased oxidative stress and loss of retinal ganglion cells (RGCs). Whether Hhcy is causative or merely a biomarker for RGC loss in glaucoma is un...

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Détails bibliographiques
Publié dans:Redox Biol
Auteurs principaux: Navneet, Soumya, Zhao, Jing, Wang, Jing, Mysona, Barbara, Barwick, Shannon, Ammal Kaidery, Navneet, Saul, Alan, Kaddour-Djebbar, Ismail, Bollag, Wendy B., Thomas, Bobby, Bollinger, Kathryn E., Smith, Sylvia B.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482349/
https://ncbi.nlm.nih.gov/pubmed/31026769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101199
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