Interferon stimulation creates chromatin marks and establishes transcriptional memory

Epigenetic memory for signal-dependent transcription has remained elusive. So far, the concept of epigenetic memory has been largely limited to cell-autonomous, preprogrammed processes such as development and metabolism. Here we show that IFNβ stimulation creates transcriptional memory in fibroblast...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Kamada, Rui, Yang, Wenjing, Zhang, Yubo, Patel, Mira C., Yang, Yanqin, Ouda, Ryota, Dey, Anup, Wakabayashi, Yoshiyuki, Sakaguchi, Kazuyasu, Fujita, Takashi, Tamura, Tomohiko, Zhu, Jun, Ozato, Keiko
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2018
Ábhair:
PNAS Plus
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166839/
https://ncbi.nlm.nih.gov/pubmed/30201712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720930115
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