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Activation of JNK Triggers Release of Brd4 from Mitotic Chromosomes and Mediates Protection from Drug-Induced Mitotic Stress

Some anti-cancer drugs, including those that alter microtubule dynamics target mitotic cells and induce apoptosis in some cell types. However, such drugs elicit protective responses in other cell types allowing cells to escape from drug-induced mitotic inhibition. Cells with a faulty protective mech...

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Autors principals: Nishiyama, Akira, Dey, Anup, Tamura, Tomohiko, Ko, Minoru, Ozato, Keiko
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342290/
https://ncbi.nlm.nih.gov/pubmed/22567088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034719
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