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Activation of JNK Triggers Release of Brd4 from Mitotic Chromosomes and Mediates Protection from Drug-Induced Mitotic Stress

Some anti-cancer drugs, including those that alter microtubule dynamics target mitotic cells and induce apoptosis in some cell types. However, such drugs elicit protective responses in other cell types allowing cells to escape from drug-induced mitotic inhibition. Cells with a faulty protective mech...

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Détails bibliographiques
Auteurs principaux: Nishiyama, Akira, Dey, Anup, Tamura, Tomohiko, Ko, Minoru, Ozato, Keiko
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342290/
https://ncbi.nlm.nih.gov/pubmed/22567088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034719
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