Tissue plasminogen activator promotes white matter integrity and functional recovery in a murine model of traumatic brain injury

Recombinant tissue plasminogen activator (tPA) is a Food and Drug Administration-approved thrombolytic treatment for ischemic stroke. tPA is also naturally expressed in glial and neuronal cells of the brain, where it promotes axon outgrowth and synaptic plasticity. However, there are conflicting rep...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Xia, Yuguo, Pu, Hongjian, Leak, Rehana K., Shi, Yejie, Mu, Hongfeng, Hu, Xiaoming, Lu, Zhengyu, Foley, Lesley M., Hitchens, T. Kevin, Dixon, C. Edward, Bennett, Michael V. L., Chen, Jun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2018
Aiheet:
PNAS Plus
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166834/
https://ncbi.nlm.nih.gov/pubmed/30201709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1810693115
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