Systematic mapping of free energy landscapes of a growing filamin domain during biosynthesis

Cotranslational folding (CTF) is a fundamental molecular process that ensures efficient protein biosynthesis and minimizes the formation of misfolded states. However, the complexity of this process makes it extremely challenging to obtain structural characterizations of CTF pathways. Here, we correl...

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Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Waudby, Christopher A., Wlodarski, Tomasz, Karyadi, Maria-Evangelia, Cassaignau, Anaïs M. E., Chan, Sammy H. S., Wentink, Anne S., Schmidt-Engler, Julian M., Camilloni, Carlo, Vendruscolo, Michele, Cabrita, Lisa D., Christodoulou, John
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166796/
https://ncbi.nlm.nih.gov/pubmed/30201720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716252115
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