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The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein
Co-translational folding is crucial to ensure the production of biologically active proteins. The ribosome can alter the folding pathways of nascent polypeptide chains, yet a structural understanding remains largely inaccessible experimentally. We have developed site-specific labelling of nascent ch...
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| Udgivet i: | Nat Chem |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2022
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613651/ https://ncbi.nlm.nih.gov/pubmed/35927328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-022-01004-0 |
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