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The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein

Co-translational folding is crucial to ensure the production of biologically active proteins. The ribosome can alter the folding pathways of nascent polypeptide chains, yet a structural understanding remains largely inaccessible experimentally. We have developed site-specific labelling of nascent ch...

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Detalhes bibliográficos
Publicado no:Nat Chem
Main Authors: Chan, Sammy H. S., Włodarski, Tomasz, Streit, Julian O., Cassaignau, Anaïs M. E., Woodburn, Lauren F., Ahn, Minkoo, Freiherr von Sass, Georg Johannes, Waudby, Christopher A., Budisa, Nediljko, Cabrita, Lisa D., Christodoulou, John
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2022
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613651/
https://ncbi.nlm.nih.gov/pubmed/35927328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-022-01004-0
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