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Systematic mapping of free energy landscapes of a growing filamin domain during biosynthesis

Cotranslational folding (CTF) is a fundamental molecular process that ensures efficient protein biosynthesis and minimizes the formation of misfolded states. However, the complexity of this process makes it extremely challenging to obtain structural characterizations of CTF pathways. Here, we correl...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Waudby, Christopher A., Wlodarski, Tomasz, Karyadi, Maria-Evangelia, Cassaignau, Anaïs M. E., Chan, Sammy H. S., Wentink, Anne S., Schmidt-Engler, Julian M., Camilloni, Carlo, Vendruscolo, Michele, Cabrita, Lisa D., Christodoulou, John
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166796/
https://ncbi.nlm.nih.gov/pubmed/30201720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716252115
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