Distinct substrate specificities of human GlcNAc-6-sulfotransferases revealed by mass spectrometry–based sulfoglycomic analysis

Sulfated glycans are known to be involved in several glycan-mediated cell adhesion and recognition pathways. Our mRNA transcript analyses on the genes involved in synthesizing GlcNAc-6-O–sulfated glycans in human colon cancer tissues indicated that GlcNAc6ST-2 (CHST4) is preferentially expressed in...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Yu, Shin-Yi, Hsiao, Cheng-Te, Izawa, Mineko, Yusa, Akiko, Ishida, Hiroji, Nakamura, Shigeo, Yagi, Hirokazu, Kannagi, Reiji, Khoo, Kay-Hooi
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2018
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166739/
https://ncbi.nlm.nih.gov/pubmed/30093410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001937
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