Llwytho...

Multiple Domains of GlcNAc-1-phosphotransferase Mediate Recognition of Lysosomal Enzymes

The Golgi enzyme UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-1-phosphotransferase), an α(2)β(2)γ(2) hexamer, mediates the initial step in the addition of the mannose 6-phosphate targeting signal on newly synthesized lysosomal enzymes. This tag serves to direct the ly...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: van Meel, Eline, Lee, Wang-Sik, Liu, Lin, Qian, Yi, Doray, Balraj, Kornfeld, Stuart
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825028/
https://ncbi.nlm.nih.gov/pubmed/26833567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.714568
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