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Role of Spacer-1 in the Maturation and Function of GlcNAc-1-Phosphotransferase
UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-1-PT) is an α(2)β(2)γ(2) hexamer that mediates the initial step in the formation of the mannose 6-phosphate targeting signal on newly synthesized lysosomal acid hydrolases. The GNPTAB gene encodes the 1256 amino acid long α...
Gardado en:
| Publicado en: | FEBS Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5235957/ https://ncbi.nlm.nih.gov/pubmed/27981560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12525 |
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