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Role of Spacer-1 in the Maturation and Function of GlcNAc-1-Phosphotransferase

UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-1-PT) is an α(2)β(2)γ(2) hexamer that mediates the initial step in the formation of the mannose 6-phosphate targeting signal on newly synthesized lysosomal acid hydrolases. The GNPTAB gene encodes the 1256 amino acid long α...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FEBS Lett
Egile Nagusiak: Liu, Lin, Lee, Wang-Sik, Doray, Balraj, Kornfeld, Stuart
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5235957/
https://ncbi.nlm.nih.gov/pubmed/27981560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12525
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