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The contribution of cross-talk between the cell-surface proteins CD36 and CD47–TSP-1 in osteoclast formation and function
Antibody-mediated blockade of cluster of differentiation 47 (CD47)–thrombospondin-1 (TSP-1) interactions blocks osteoclast formation in vitro and attenuates parathyroid hormone (PTH)-induced hypercalcemia in vivo in mice. Hypercalcemia in this model reflects increased bone resorption. TSP-1 has two...
Gardado en:
| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6166722/ https://ncbi.nlm.nih.gov/pubmed/30082316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000633 |
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