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Observing Single-Molecule Dynamics at Millimolar Concentrations

Single-molecule fluorescence microscopy is a powerful tool for revealing chemical dynamics and molecular association mechanisms, but was limited to low concentrations of fluorescent species only suitable for studying high affinity reactions. Here, we combine nanophotonic zero-mode waveguides (ZMW) w...

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Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Goldschen-Ohm, Marcel P., White, David S., Klenchin, Vadim A., Chanda, Baron, Goldsmith, Randall H.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166642/
https://ncbi.nlm.nih.gov/pubmed/28116856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201612050
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