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Observing Single-Molecule Dynamics at Millimolar Concentrations
Single-molecule fluorescence microscopy is a powerful tool for revealing chemical dynamics and molecular association mechanisms, but was limited to low concentrations of fluorescent species only suitable for studying high affinity reactions. Here, we combine nanophotonic zero-mode waveguides (ZMW) w...
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| Publié dans: | Angew Chem Int Ed Engl |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6166642/ https://ncbi.nlm.nih.gov/pubmed/28116856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201612050 |
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