Φορτώνει......
Gain-of-function Shh mutants activate Smo cell-autonomously independent of Ptch1/2 function
Sonic Hedgehog (Shh) signaling is characterized by non-cell autonomy; cells expressing Shh do not respond to the ligand. Here, we identify several Shh mutations that can activate the Hedgehog (Hh) pathway cell-autonomously. Cell-autonomous pathway activation requires the extracellular cysteine rich...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mech Dev |
|---|---|
| Κύριοι συγγραφείς: | , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6165682/ https://ncbi.nlm.nih.gov/pubmed/30144507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2018.08.009 |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|