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Mechanical stretch induces antioxidant responses and osteogenic differentiation in human mesenchymal stem cells through activation of the AMPK-SIRT1 signaling pathway

Mesenchymal stem cells (MSCs) are promising cell sources for regenerative medicine. Growing evidence has indicated that mechanical stimuli are crucial for their lineage-specific differentiation. However, the effect of mechanical loading on redox balance and the intracellular antioxidant system in MS...

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Podrobná bibliografie
Vydáno v:Free Radic Biol Med
Hlavní autoři: Chen, Xi, Yan, Jinku, He, Fan, Zhong, Dongyan, Yang, Huilin, Pei, Ming, Luo, Zong-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6165675/
https://ncbi.nlm.nih.gov/pubmed/30096433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2018.08.001
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